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The purpose of this study was to evaluate the bone age and hand anomaly in Down syndrome patients. We reviewed radiographs in 52 children and youths with Down syndrome, aged from 2 to 23 years. The characteristic findings of hand anomaly were observed in the middle phalanx of the fifth finger, with the fol1owing incidence; brachymesophalangia (44%), clinodactyly(48%), and  dysmesophalangia  (15%).

Pseudoepiphysis(21%) was found typically at the distal end of the first metacarpal bone and proximal end of the second metacarpal bone. Up to 8.5 years of age, bone maturation was retarded and thereafter bone age accelarated in advance of chrono1ogic  age. These findings may provide valuable information relative to the diagnosis and treatment of hand anomaly in Down syndrome.

Key Words: Down Syndrome, Hand Anomaly, Bone Age