임덕우,
박정훈, 김현진, 이무형 대피지 2002년 40권
7호 801 ~ 806
Background:
Syringoma is a relatively common benign appendageal
tumor derived from the intraepidermal eccrine ducts.
It occurs predominantly in women at puberty or later
in life. The lesions usually are multiple an d may
be present in great numbers. Histopathologically,
numerous small ducts are embedded in a fibrous stroma
and their walls are lined by two rows of epithelial
cells.
Objective:
The aim of this study is to investigate clinical
and histopathologic features of syringoma in Koreans.
Methods:
Total 32 patients were included in this study. Data
complied were sex, age, onset of disease, symptoms,
family history, localization, distribution, and
some histopathologic findings including acanthosis,
basal hyperpigmentation, proliferation of fibrous
stroma, vacuolization of cells, keratin-filled cyst,
and characteristic tad-pole appearance.
Results:
1.
It was observed predominantly in females as the
sex ratio of 31:1. The mean age at diagnosis was
37.5-years-old.
2.
The age of onset was in the 2nd decade in 9 patients,
3rd decade in 10 patients, 4th decade in 7 patients,
5th decade in 5 patients, and 7th decade in 1 patient.
3.
Only two patients complained of mild itching.
4.
Family history was noted in 14 patients.
5.
It occurred most frequently in the upper and lower
eyelids(28 cases), and followed by forehead(5 cases),
genitalia(3 cases), temple(2 cases), cheek(1 case),
and neck(1 case).
6.
The distribution was bilateral except two patients.
7.
The color of lesion showed skin-colored(23 cases),
yellowish(6 cases), and brownish (3 cases).
8.
Twelve cases of acanthosis, 11 cases of basal hyperpigmentation,
26 cases of proliferation of fibrous stroma, 13
cases showing vacuolization of inner cell layer
of ducts, 8 cases showing keratin-filled cysts and
15 cases showing characteristic tad-pole appearance
were observed.
Conclusion:
According to our study, syringoma predominantly
occurs in eyelids of women as bilateral asymptomatic
skin-colored papules and histopathologic findings
frequently shows keratin-filled cysts. |
