김현진,
이무형 대피지 2002년 40권 12호 1543
~ 1546
The
etiology of scleroderma remains uncertain, but several
pathomechanisms have been suggested including vascular
alterations with endothelial cell damage, disturbances
in the control of collagen synthesis and autoimmune
activity. The association with other autoimmune
diseases such as thyroid disorder and vitiligo may
favor the attribution of autoimmunity to its pathomechanism.
But their association has been rarely reported.
Psoralen
plus ultraviolet A (PUVA) photochemotherapy is the
most popular and effective therapeutic modality
for vitiligo. And successful treatments of localized
scleroderma with PUVA photochemotherapy have been
reported, including topical, systemic, and bath
PUVA.
We
report a case of successful treatment with low-dose
systemic PUVA photochemotherapy for the patient,
who has concurrently both the localized scleroderma
and vitiligo. |
