김휘준,
임덕우 이무형 대피지 2001년 39권 6호
734 ~ 735
Ketoprofen,
a propionic acid derivative is a non-steroidal anti-inflammatory
drug with analgesic activity and it is used in the
symptomatic treatment of rheumatoid arthritis and
osteoarthritis. When exposed to sunlight, k etoprofen
is broken down into various benzophenones. 3-ethyl-benzophenone
as the major photoproduct is responsible for the
photoallergic reaction to ketoprofen. A 30-year-old
male presented with well-demarcated erythematous
patches with itching sensation on both his ankle
areas. He had applied Ketotop plasters on both his
ankle areas for arthralgia, and then the Ketotop
plaster-detached areas were exposed to sunlight.
Patch test and photopatch test withas isshowed positive
reaction in photopatch test and the ingredients
of Ketotop plaster revealed positive reaction to
the ketoprofen contained in Ketotop plaster in photopatch
test. |
