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Urokinase Injection through the Percutaneous Drainage Catheter to the Multiply Septated Liver Abscess, Subhepatic Abscess, and Retroperitoneal Hematoma
Sang Soo Kim, M.D, Young Gwan Ko, M.D,, Sang Mok Lee, M.D., Sung Wha Hong M. D, Choong Yoon, M.D., Hoong Zae Joo, M. D. and Joo Hyeong Oh, M.D*.
Department of Surgery and Radio1ogy*, Kyung Hee University Hospital, Seoul, Korea

 

Although, Percutaneous drainage of abscesses is an effective treatment, the success rate for abscesses that have septa and are multilocular is lower. Several clinical and in-vitro studies suggest that urokinase may be useful in such cases.

We experienced three patients undergone percutaneous drainage and intracavitary urokinase injection through the drainage catheter. One patient is with liver abscess which is multiloculated by septa. We hardly draw out the abscess with usual percutaneous drainage catheter only. But with injection of urokinase through the drainage catheter, we could get a successful result. Other two patients, subhepatic abscess and retroperitoneal hematoma, also could get good results with urokinase injection through the percutaneous drainage catheter without complications. Conclusion ; Intracavitary urokinase can be given safely during percutaneous drainage of all abscess, without bleeding complication or change in coagulation parameters.