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1999;37;12 1808-1812
Kyrle's
disease is a rare disorder characterized by hyperkeratotic papules containing a
central, cone-shaped plug on the extensor surface of the extremites. We describe
two cases of Kyrle's disease. The first case is 65-year-old male patient. He had
multiple pruritic hyperkeratotic papules with a central plug on both lower extremities.
He has suffered from Diabetes mellitus for 20 years. The second case is 54-year-old
male patient. He had multiple pruritic hyperkeratotic papules with a central plug
on the back, upper and lower extremities. He has been suffered from Diabetes mellitus
for 20 years and chronic renal failure for 6 months. Histopathologic findings showed
central epidermal invagination filled with heavy keratotic, partly parakeratotic
plug and basophilic debries. Many vacuolated cells and a few dyskeratotic cells
were seen below the keratotic plug. |